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MCMC-ODPR: Primer design optimization using Markov Chain Monte Carlo sampling
BACKGROUND: Next generation sequencing technologies often require numerous primer designs that require good target coverage that can be financially costly. We aimed to develop a system that would implement primer reuse to design degenerate primers that could be designed around SNPs, thus find the fe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561117/ https://www.ncbi.nlm.nih.gov/pubmed/23126469 http://dx.doi.org/10.1186/1471-2105-13-287 |