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HIF- and Non-HIF-Regulated Hypoxic Responses Require the Estrogen-Related Receptor in Drosophila melanogaster

Low-oxygen tolerance is supported by an adaptive response that includes a coordinate shift in metabolism and the activation of a transcriptional program that is driven by the hypoxia-inducible factor (HIF) pathway. The precise contribution of HIF-1a in the adaptive response, however, has not been de...

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Detalles Bibliográficos
Autores principales: Li, Yan, Padmanabha, Divya, Gentile, Luciana B., Dumur, Catherine I., Beckstead, Robert B., Baker, Keith D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561118/
https://www.ncbi.nlm.nih.gov/pubmed/23382692
http://dx.doi.org/10.1371/journal.pgen.1003230