Preclinical evaluation of carbon-11 and fluorine-18 sulfonamide derivatives for in vivo radiolabeling of erythrocytes

BACKGROUND: To date, few PET tracers for in vivo labeling of red blood cells (RBCs) are available. In this study, we report the radiosynthesis and in vitro and in vivo evaluation of (11)C and (18)F sulfonamide derivatives targeting carbonic anhydrase II (CA II), a metallo-enzyme expressed in RBCs, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gheysens, Olivier, Akurathi, Vamsidhar, Chekol, Rufael, Dresselaers, Tom, Celen, Sofie, Koole, Michel, Dauwe, Dieter, Cleynhens, Bernard J, Claus, Piet, Janssens, Stefan, Verbruggen, Alfons M, Nuyts, Johan, Himmelreich, Uwe, Bormans, Guy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561128/
https://www.ncbi.nlm.nih.gov/pubmed/23316861
http://dx.doi.org/10.1186/2191-219X-3-4

Ejemplares similares

Ejemplares similares