Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis

Iron is an essential nutrient for most bacterial pathogens, but is restricted by the host immune system. Mycobacterium tuberculosis (Mtb) utilizes two classes of small molecules, mycobactins and carboxymycobactins, to capture iron from the human host. Here, we show that an Mtb mutant lacking the mmp...

Descripción completa

Detalles Bibliográficos
Autores principales: Wells, Ryan M., Jones, Christopher M., Xi, Zhaoyong, Speer, Alexander, Danilchanka, Olga, Doornbos, Kathryn S., Sun, Peibei, Wu, Fangming, Tian, Changlin, Niederweis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561183/
https://www.ncbi.nlm.nih.gov/pubmed/23431276
http://dx.doi.org/10.1371/journal.ppat.1003120

Ejemplares similares

Ejemplares similares