TLR-4 engagement of dendritic cells confers a BST-2/tetherin-mediated restriction of HIV-1 infection to CD4(+) T cells across the virological synapse

BACKGROUND: Dendritic cells and their subsets, located at mucosal surfaces, are among the first immune cells to encounter disseminating pathogens. The cellular restriction factor BST-2/tetherin (also known as CD317 or HM1.24) potently restricts HIV-1 release by retaining viral particles at the cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Blanchet, Fabien P, Stalder, Romaine, Czubala, Magdalena, Lehmann, Martin, Rio, Laura, Mangeat, Bastien, Piguet, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561259/
https://www.ncbi.nlm.nih.gov/pubmed/23311681
http://dx.doi.org/10.1186/1742-4690-10-6

Ejemplares similares

Ejemplares similares