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MeCP2 modulates gene expression pathways in astrocytes

BACKGROUND: Mutations in MECP2 encoding methyl-CpG-binding protein 2 (MeCP2) cause the X-linked neurodevelopmental disorder Rett syndrome. Rett syndrome patients exhibit neurological symptoms that include irregular breathing, impaired mobility, stereotypic hand movements, and loss of speech. MeCP2 p...

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Detalles Bibliográficos
Autores principales: Yasui, Dag H, Xu, Huichun, Dunaway, Keith W, LaSalle, Janine M, Jin, Lee-Way, Maezawa, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561260/
https://www.ncbi.nlm.nih.gov/pubmed/23351786
http://dx.doi.org/10.1186/2040-2392-4-3