Cargando…
MeCP2 modulates gene expression pathways in astrocytes
BACKGROUND: Mutations in MECP2 encoding methyl-CpG-binding protein 2 (MeCP2) cause the X-linked neurodevelopmental disorder Rett syndrome. Rett syndrome patients exhibit neurological symptoms that include irregular breathing, impaired mobility, stereotypic hand movements, and loss of speech. MeCP2 p...
Autores principales: | Yasui, Dag H, Xu, Huichun, Dunaway, Keith W, LaSalle, Janine M, Jin, Lee-Way, Maezawa, Izumi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561260/ https://www.ncbi.nlm.nih.gov/pubmed/23351786 http://dx.doi.org/10.1186/2040-2392-4-3 |
Ejemplares similares
-
The Role of MeCP2 in Brain Development and Neurodevelopmental Disorders
por: Gonzales, Michael L., et al.
Publicado: (2010) -
Sequence features accurately predict genome-wide MeCP2 binding in vivo
por: Rube, H. Tomas, et al.
Publicado: (2016) -
The Molecular Functions of MeCP2 in Rett Syndrome Pathology
por: Sharifi, Osman, et al.
Publicado: (2021) -
Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome
por: Veeraragavan, Surabi, et al.
Publicado: (2016) -
Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism
por: Swanberg, Susan E., et al.
Publicado: (2009)