Pan-histone deacetylase inhibitors regulate signaling pathways involved in proliferative and pro-inflammatory mechanisms in H9c2 cells

BACKGROUND: We have shown previously that pan-HDAC inhibitors (HDACIs) m-carboxycinnamic acid bis-hydroxamide (CBHA) and trichostatin A (TSA) attenuated cardiac hypertrophy in BALB/c mice by inducing hyper-acetylation of cardiac chromatin that was accompanied by suppression of pro-inflammatory gene...

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Detalles Bibliográficos
Autores principales: Majumdar, Gipsy, Adris, Piyatilake, Bhargava, Neha, Chen, Hao, Raghow, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561284/
https://www.ncbi.nlm.nih.gov/pubmed/23249388
http://dx.doi.org/10.1186/1471-2164-13-709

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