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Over-Expressing Mitofusin-2 in Healthy Mature Mammalian Skeletal Muscle Does Not Alter Mitochondrial Bioenergetics
The role of mitofusin-2 (MFN-2) in regulating mitochondrial dynamics has been well-characterized in lower order eukaryotic cell lines through the complete ablation of MFN-2 protein. However, to support the contractile function of mature skeletal muscle, the subcellular architecture and constituent p...
Autores principales: | Lally, James S. V., Herbst, Eric A. F., Matravadia, Sarthak, Maher, Amy C., Perry, Christopher G. R., Ventura-Clapier, Renée, Holloway, Graham P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561349/ https://www.ncbi.nlm.nih.gov/pubmed/23383258 http://dx.doi.org/10.1371/journal.pone.0055660 |
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