Exome Sequencing of Germline DNA from Non-BRCA1/2 Familial Breast Cancer Cases Selected on the Basis of aCGH Tumor Profiling

The bulk of familial breast cancer risk (∼70%) cannot be explained by mutations in the known predisposition genes, primarily BRCA1 and BRCA2. Underlying genetic heterogeneity in these cases is the probable explanation for the failure of all attempts to identify further high-risk alleles. While exome...

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Detalles Bibliográficos
Autores principales: Hilbers, Florentine S., Meijers, Caro M., Laros, Jeroen F. J., van Galen, Michiel, Hoogerbrugge, Nicoline, Vasen, Hans F. A., Nederlof, Petra M., Wijnen, Juul T., van Asperen, Christi J., Devilee, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561352/
https://www.ncbi.nlm.nih.gov/pubmed/23383274
http://dx.doi.org/10.1371/journal.pone.0055734

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