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Efficient Generation of Rat Induced Pluripotent Stem Cells Using a Non-Viral Inducible Vector

Current methods of generating rat induced pluripotent stem cells are based on viral transduction of pluripotency inducing genes (Oct4, Sox2, c-myc and Klf4) into somatic cells. These activate endogenous pluripotency genes and reprogram the identity of the cell to an undifferentiated state. Epigeneti...

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Detalles Bibliográficos
Autores principales:	Merkl, Claudia, Saalfrank, Anja, Riesen, Nathalie, Kühn, Ralf, Pertek, Anna, Eser, Stefan, Hardt, Markus Sebastian, Kind, Alexander, Saur, Dieter, Wurst, Wolfgang, Iglesias, Antonio, Schnieke, Angelika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561372/ https://www.ncbi.nlm.nih.gov/pubmed/23383095 http://dx.doi.org/10.1371/journal.pone.0055170

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