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Genetically Matched Human iPS Cells Reveal that Propensity for Cartilage and Bone Differentiation Differs with Clones, not Cell Type of Origin

BACKGROUND: For regenerative therapy using induced pluripotent stem cell (iPSC) technology, cell type of origin to be reprogrammed should be chosen based on accessibility and reprogramming efficiency. Some studies report that iPSCs exhibited a preference for differentiation into their original cell...

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Detalles Bibliográficos
Autores principales: Nasu, Akira, Ikeya, Makoto, Yamamoto, Takuya, Watanabe, Akira, Jin, Yonghui, Matsumoto, Yoshihisa, Hayakawa, Kazuo, Amano, Naoki, Sato, Shingo, Osafune, Kenji, Aoyama, Tomoki, Nakamura, Takashi, Kato, Tomohisa, Toguchida, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561398/
https://www.ncbi.nlm.nih.gov/pubmed/23382851
http://dx.doi.org/10.1371/journal.pone.0053771