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Elevation of S100A4 Expression in Buccal Mucosal Fibroblasts by Arecoline: Involvement in the Pathogenesis of Oral Submucous Fibrosis

BACKGROUND: S100A4, a member of the calcium-binding proteins, is dramatically elevated in a variety of fibrotic diseases. Areca quid chewing is the most important etiological factor in the pathogenesis of oral submucous fibrosis (OSF). OSF has been considered as a pre-cancerous condition of oral muc...

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Detalles Bibliográficos
Autores principales: Yu, Cheng-Chia, Tsai, Chung-Hung, Hsu, Hsin-I, Chang, Yu-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561403/
https://www.ncbi.nlm.nih.gov/pubmed/23383075
http://dx.doi.org/10.1371/journal.pone.0055122

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