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The Function of the Conserved Regulatory Element within the Second Intron of the Mammalian Csf1r Locus
The gene encoding the receptor for macrophage colony-stimulating factor (CSF-1R) is expressed exclusively in cells of the myeloid lineages as well as trophoblasts. A conserved element in the second intron, Fms-Intronic Regulatory Element (FIRE), is essential for macrophage-specific transcription of...
Autores principales: | Sauter, Kristin A., Bouhlel, M. Amine, O’Neal, Julie, Sester, David P., Tagoh, Hiromi, Ingram, Richard M., Pridans, Clare, Bonifer, Constanze, Hume, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561417/ https://www.ncbi.nlm.nih.gov/pubmed/23383005 http://dx.doi.org/10.1371/journal.pone.0054935 |
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