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Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats
Brown Norway rats (BN, BN/NHsdMcwi) are profoundly resistant to developing acute kidney injury (AKI) following ischemia reperfusion. To help define the genetic basis for this resistance, we used consomic rats, in which individual chromosomes from BN rats were placed into the genetic background of Da...
Autores principales: | Basile, David P., Dwinell, Melinda R., Wang, Shur-Jen, Shames, Brian D., Donohoe, Deborah, Chen, Shaoying, Sreedharan, Rajasree, Van Why, Scott K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561482/ https://www.ncbi.nlm.nih.gov/pubmed/23235564 http://dx.doi.org/10.1038/ki.2012.391 |
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