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Distinct Roles in Autophagy and Importance in Infectivity of the Two ATG4 Cysteine Peptidases of Leishmania major

Macroautophagy in Leishmania, which is important for the cellular remodeling required during differentiation, relies upon the hydrolytic activity of two ATG4 cysteine peptidases (ATG4.1 and ATG4.2). We have investigated the individual contributions of each ATG4 to Leishmania major by generating indi...

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Detalles Bibliográficos
Autores principales:	Williams, Roderick A. M., Mottram, Jeremy C., Coombs, Graham H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561585/ https://www.ncbi.nlm.nih.gov/pubmed/23166325 http://dx.doi.org/10.1074/jbc.M112.415372

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