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Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer

Endometrial cancer is the most frequent cancer of female genital tract. Metro- and menorrhagia or postmenopausal bleeding results in its early presentation. It allows radical treatment. However, controversies remain on surgery coverage or adjuvant therapies in early endometrial women cancer. Optimal...

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Detalles Bibliográficos
Autores principales: Kellas-Ślęczka, Sylwia, Wojcieszek, Piotr, Białas, Brygida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561608/
https://www.ncbi.nlm.nih.gov/pubmed/23378855
http://dx.doi.org/10.5114/jcb.2012.32560
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author Kellas-Ślęczka, Sylwia
Wojcieszek, Piotr
Białas, Brygida
author_facet Kellas-Ślęczka, Sylwia
Wojcieszek, Piotr
Białas, Brygida
author_sort Kellas-Ślęczka, Sylwia
collection PubMed
description Endometrial cancer is the most frequent cancer of female genital tract. Metro- and menorrhagia or postmenopausal bleeding results in its early presentation. It allows radical treatment. However, controversies remain on surgery coverage or adjuvant therapies in early endometrial women cancer. Optimal management should minimize intervention instead of aggressive approach, as showed by recent studies. There is a role for brachytherapy as an adjuvant irradiation. Crucial publications including PORTEC-1, GOG 99, MRC ASTEC, ASTEC/EN.5, PORTEC-2 or Italian lymphadenectomy trial are discussed. Moreover, there is attention paid on adjuvant vaginal brachytherapy analyses for the past fifteen years.
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spelling pubmed-35616082013-02-01 Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer Kellas-Ślęczka, Sylwia Wojcieszek, Piotr Białas, Brygida J Contemp Brachytherapy Review Article Endometrial cancer is the most frequent cancer of female genital tract. Metro- and menorrhagia or postmenopausal bleeding results in its early presentation. It allows radical treatment. However, controversies remain on surgery coverage or adjuvant therapies in early endometrial women cancer. Optimal management should minimize intervention instead of aggressive approach, as showed by recent studies. There is a role for brachytherapy as an adjuvant irradiation. Crucial publications including PORTEC-1, GOG 99, MRC ASTEC, ASTEC/EN.5, PORTEC-2 or Italian lymphadenectomy trial are discussed. Moreover, there is attention paid on adjuvant vaginal brachytherapy analyses for the past fifteen years. Termedia Publishing House 2012-12-28 2012-12 /pmc/articles/PMC3561608/ /pubmed/23378855 http://dx.doi.org/10.5114/jcb.2012.32560 Text en Copyright © 2012 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kellas-Ślęczka, Sylwia
Wojcieszek, Piotr
Białas, Brygida
Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
title Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
title_full Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
title_fullStr Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
title_full_unstemmed Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
title_short Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
title_sort adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561608/
https://www.ncbi.nlm.nih.gov/pubmed/23378855
http://dx.doi.org/10.5114/jcb.2012.32560
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