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Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer
Endometrial cancer is the most frequent cancer of female genital tract. Metro- and menorrhagia or postmenopausal bleeding results in its early presentation. It allows radical treatment. However, controversies remain on surgery coverage or adjuvant therapies in early endometrial women cancer. Optimal...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561608/ https://www.ncbi.nlm.nih.gov/pubmed/23378855 http://dx.doi.org/10.5114/jcb.2012.32560 |
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author | Kellas-Ślęczka, Sylwia Wojcieszek, Piotr Białas, Brygida |
author_facet | Kellas-Ślęczka, Sylwia Wojcieszek, Piotr Białas, Brygida |
author_sort | Kellas-Ślęczka, Sylwia |
collection | PubMed |
description | Endometrial cancer is the most frequent cancer of female genital tract. Metro- and menorrhagia or postmenopausal bleeding results in its early presentation. It allows radical treatment. However, controversies remain on surgery coverage or adjuvant therapies in early endometrial women cancer. Optimal management should minimize intervention instead of aggressive approach, as showed by recent studies. There is a role for brachytherapy as an adjuvant irradiation. Crucial publications including PORTEC-1, GOG 99, MRC ASTEC, ASTEC/EN.5, PORTEC-2 or Italian lymphadenectomy trial are discussed. Moreover, there is attention paid on adjuvant vaginal brachytherapy analyses for the past fifteen years. |
format | Online Article Text |
id | pubmed-3561608 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-35616082013-02-01 Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer Kellas-Ślęczka, Sylwia Wojcieszek, Piotr Białas, Brygida J Contemp Brachytherapy Review Article Endometrial cancer is the most frequent cancer of female genital tract. Metro- and menorrhagia or postmenopausal bleeding results in its early presentation. It allows radical treatment. However, controversies remain on surgery coverage or adjuvant therapies in early endometrial women cancer. Optimal management should minimize intervention instead of aggressive approach, as showed by recent studies. There is a role for brachytherapy as an adjuvant irradiation. Crucial publications including PORTEC-1, GOG 99, MRC ASTEC, ASTEC/EN.5, PORTEC-2 or Italian lymphadenectomy trial are discussed. Moreover, there is attention paid on adjuvant vaginal brachytherapy analyses for the past fifteen years. Termedia Publishing House 2012-12-28 2012-12 /pmc/articles/PMC3561608/ /pubmed/23378855 http://dx.doi.org/10.5114/jcb.2012.32560 Text en Copyright © 2012 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Kellas-Ślęczka, Sylwia Wojcieszek, Piotr Białas, Brygida Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer |
title | Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer |
title_full | Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer |
title_fullStr | Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer |
title_full_unstemmed | Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer |
title_short | Adjuvant vaginal brachytherapy as a part of management in early endometrial cancer |
title_sort | adjuvant vaginal brachytherapy as a part of management in early endometrial cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561608/ https://www.ncbi.nlm.nih.gov/pubmed/23378855 http://dx.doi.org/10.5114/jcb.2012.32560 |
work_keys_str_mv | AT kellassleczkasylwia adjuvantvaginalbrachytherapyasapartofmanagementinearlyendometrialcancer AT wojcieszekpiotr adjuvantvaginalbrachytherapyasapartofmanagementinearlyendometrialcancer AT białasbrygida adjuvantvaginalbrachytherapyasapartofmanagementinearlyendometrialcancer |