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Circulating human basophils lack the features of professional antigen presenting cells

Recent reports in mice demonstrate that basophils function as antigen presenting cells (APC). They express MHC class II and co-stimulatory molecules CD80 and CD86, capture and present soluble antigens or IgE-antigen complexes and polarize Th2 responses. Therefore, we explored whether human circulati...

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Detalles Bibliográficos
Autores principales: Sharma, Meenu, Hegde, Pushpa, Aimanianda, Vishukumar, Beau, Remi, Sénéchal, Helene, Poncet, Pascal, Latgé, Jean-Paul, Kaveri, Srini V., Bayry, Jagadeesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561623/
https://www.ncbi.nlm.nih.gov/pubmed/23378919
http://dx.doi.org/10.1038/srep01188