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Circulating human basophils lack the features of professional antigen presenting cells
Recent reports in mice demonstrate that basophils function as antigen presenting cells (APC). They express MHC class II and co-stimulatory molecules CD80 and CD86, capture and present soluble antigens or IgE-antigen complexes and polarize Th2 responses. Therefore, we explored whether human circulati...
Autores principales: | Sharma, Meenu, Hegde, Pushpa, Aimanianda, Vishukumar, Beau, Remi, Sénéchal, Helene, Poncet, Pascal, Latgé, Jean-Paul, Kaveri, Srini V., Bayry, Jagadeesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561623/ https://www.ncbi.nlm.nih.gov/pubmed/23378919 http://dx.doi.org/10.1038/srep01188 |
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