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USP7S-dependent inactivation of Mule regulates DNA damage signalling and repair

The E3 ubiquitin ligase Mule/ARF-BP1 plays an important role in the cellular DNA damage response by controlling base excision repair and p53 protein levels. However, how the activity of Mule is regulated in response to DNA damage is currently unknown. Here, we report that the Ser18-containing isofor...

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Detalles Bibliográficos
Autores principales:	Khoronenkova, Svetlana V., Dianov, Grigory L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561956/ https://www.ncbi.nlm.nih.gov/pubmed/23275561 http://dx.doi.org/10.1093/nar/gks1359

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