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p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair
Besides the primary histone acetyltransferase (HAT)-mediated chromatin remodeling function, co-transcriptional factor, p300, is also known to play a distinct role in DNA repair. However, the exact mechanism of p300 function in DNA repair has remained unclear and difficult to discern due to the phosp...
Autores principales: | Wang, Qi-En, Han, Chunhua, Zhao, Ran, Wani, Gulzar, Zhu, Qianzheng, Gong, Li, Battu, Aruna, Racoma, Ira, Sharma, Nidhi, Wani, Altaf A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561975/ https://www.ncbi.nlm.nih.gov/pubmed/23275565 http://dx.doi.org/10.1093/nar/gks1312 |
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