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CHFR is important for the first wave of ubiquitination at DNA damage sites

Protein ubiquitination plays an important role in activating the DNA damage response and maintaining genomic stability. In response to DNA double-strand breaks (DSBs), a ubiquitination cascade occurs at DNA lesions. Here, we show that checkpoint with Forkhead-associated (FHA) and RING finger domain...

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Detalles Bibliográficos
Autores principales:	Liu, Chao, Wu, Jiaxue, Paudyal, Sharad C., You, Zhongsheng, Yu, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561977/ https://www.ncbi.nlm.nih.gov/pubmed/23268447 http://dx.doi.org/10.1093/nar/gks1278

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