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Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase

Nitrated polycyclic aromatic hydrocarbons are common environmental pollutants, of which many are mutagenic and carcinogenic. 1-Nitropyrene is the most abundant nitrated polycyclic aromatic hydrocarbon, which causes DNA damage and is carcinogenic in experimental animals. Error-prone translesion synth...

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Detalles Bibliográficos
Autores principales:	Kirouac, Kevin N., Basu, Ashis K., Ling, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561991/ https://www.ncbi.nlm.nih.gov/pubmed/23268450 http://dx.doi.org/10.1093/nar/gks1296

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