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A rare case of plasmacytoma of the ovary: a case report and literature review

OBJECTIVE: Extramedullary plasmacytomas are rare. Ovarian plasmacytomas, for which treatment options vary, are more unique and even more rare. We will consider the option of optimal cytoreductive surgery followed by adjuvant chemotherapy consisting of carboplatin (AUC-2) to prevent massive ascites a...

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Detalles Bibliográficos
Autores principales: Shakuntala, PN, Praveen, SR, Shankaranand, B, Rajshekar, K, Umadevi, K, Bafna, UD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562058/
https://www.ncbi.nlm.nih.gov/pubmed/23390453
http://dx.doi.org/10.3332/ecancer.2013.288
Descripción
Sumario:OBJECTIVE: Extramedullary plasmacytomas are rare. Ovarian plasmacytomas, for which treatment options vary, are more unique and even more rare. We will consider the option of optimal cytoreductive surgery followed by adjuvant chemotherapy consisting of carboplatin (AUC-2) to prevent massive ascites and pleural effusion. CASE REPORT: We report a case of ovarian plasmacytoma in a 35-year-old woman presenting with abdominal pain due to the mass. She underwent optimal cytoreductive surgery. A post-operative histopathologic diagnosis of ovarian plasmacytoma was confirmed. She was assigned stage IIC disease. She received three cycles of single agent carboplatin for rapidly refilling ascites and pleural effusion. Her response was dramatic. There is no evidence of recurrence clinically for more than 14 months. The patient is receiving follow-up care. CONCLUSION: Multimodality treatment comprising of optimal cytoreductive surgery followed by carboplatin-based chemotherapy is a novel observation and may be an option for the treatment of these rare tumours. This options needs to be further researched.