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Dectin-1 Is Required for Resistance to Coccidioidomycosis in Mice

We assessed the role of Dectin-1 in the immune response to the pathogenic fungus Coccidioides, both in vitro and in vivo, using mice with a targeted mutation in Clec7a. Elicited peritoneal macrophages responded to formalin-killed spherules (FKS) and alkali-treated FKS by secreting proinflammatory cy...

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Detalles Bibliográficos
Autores principales:	Viriyakosol, Suganya, Jimenez, Maria del Pilar, Gurney, Michael A., Ashbaugh, Mark E., Fierer, Joshua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562125/ https://www.ncbi.nlm.nih.gov/pubmed/23386437 http://dx.doi.org/10.1128/mBio.00597-12

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