Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics

BACKGROUND: Changes in cell shape and plasticity in cytoskeletal dynamics are critically involved in cell adhesion, migration, invasion and the overall process of metastasis. Previous work in our laboratory demonstrated that the synthetic steroid mifepristone inhibited the growth of highly metastati...

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Detalles Bibliográficos
Autores principales: Brandhagen, BreeAnn N, Tieszen, Chelsea R, Ulmer, Tara M, Tracy, Maria S, Goyeneche, Alicia A, Telleria, Carlos M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562154/
https://www.ncbi.nlm.nih.gov/pubmed/23351358
http://dx.doi.org/10.1186/1471-2407-13-35

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