Cargando…
A Reliable Way to Detect Endogenous Murine β-Amyloid
Unraveling the normal physiologic role of β-amyloid is likely crucial to understanding the pathogenesis of Alzheimer's disease. However, progress on this question is currently limited by the high background of many ELISAs for murine β-amyloid. Here, we examine the background signal of several m...
Autores principales: | Teich, Andrew F., Patel, Mitesh, Arancio, Ottavio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562188/ https://www.ncbi.nlm.nih.gov/pubmed/23383341 http://dx.doi.org/10.1371/journal.pone.0055647 |
Ejemplares similares
-
PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease
por: Teich, Andrew F., et al.
Publicado: (2016) -
An Intracellular Threonine of Amyloid-β Precursor Protein Mediates Synaptic Plasticity Deficits and Memory Loss
por: Lombino, Franco, et al.
Publicado: (2013) -
Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation
por: Yan, Shijun, et al.
Publicado: (2014) -
β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia
por: Tamayev, Robert, et al.
Publicado: (2012) -
Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer’s disease
por: Koppensteiner, Peter, et al.
Publicado: (2016)