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The “Sharp” blade against HIF-mediated metastasis
Hypoxia-inducible factors (HIFs) control cellular adaptation to oxygen deprivation. Cancer cells engage HIFs to sustain their growth in adverse conditions, thus promoting a cellular reprograming that includes metabolism, proliferation, survival and mobility. HIFs overexpression in human cancer biops...
Autores principales: | Amelio, Ivano, Melino, Gerry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562297/ https://www.ncbi.nlm.nih.gov/pubmed/23187809 http://dx.doi.org/10.4161/cc.22820 |
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