Cargando…

p63 the guardian of human reproduction

p63 is a transcriptional factor implicated in cancer and development. The presence in TP63 gene of alternative promoters allows expression of one isoform containing the N-terminal transactivation domain (TA isoform) and one N-terminal truncated isoform (ΔN isoform). Complete ablation of all p63 isof...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amelio, Ivano, Grespi, Francesca, Annicchiarico-Petruzzelli, Margherita, Melino, Gerry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562299/ https://www.ncbi.nlm.nih.gov/pubmed/23165243 http://dx.doi.org/10.4161/cc.22819

Ejemplares similares

Tissue-specific expression of p73 C-terminal isoforms in mice
por: Grespi, Francesca, et al.
Publicado: (2012)

p63 transcriptionally regulates the expression of matrix metallopeptidase 13
por: Celardo, Ivana, et al.
Publicado: (2014)

The hypoxic tumour microenvironment
por: Petrova, Varvara, et al.
Publicado: (2018)

p63 at the Crossroads between Stemness and Metastasis in Breast Cancer
por: Gatti, Veronica, et al.
Publicado: (2019)

p63 Is a Promising Marker in the Diagnosis of Unusual Skin Cancer
por: Smirnov, Artem, et al.
Publicado: (2019)

The p63 C-terminus is essential for murine oocyte integrity
por: Lena, Anna Maria, et al.
Publicado: (2021)

ΔNp63 in squamous cell carcinoma: defining the oncogenic routes affecting epigenetic landscape and tumour microenvironment
por: Gatti, Veronica, et al.
Publicado: (2019)

TAp73 transcriptionally represses BNIP3 expression
por: Petrova, Varvara, et al.
Publicado: (2015)

Caspase-1 is a novel target of p63 in tumor suppression
por: Celardo, I, et al.
Publicado: (2013)

DNA repair and aging: the impact of the p53 family
por: Nicolai, Sara, et al.
Publicado: (2015)

ZNF185 is a p63 target gene critical for epidermal differentiation and squamous cell carcinoma development
por: Smirnov, Artem, et al.
Publicado: (2018)

Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis
por: Regina, Carla, et al.
Publicado: (2016)

Commensal microbes and p53 in cancer progression
por: Celardo, Ivana, et al.
Publicado: (2020)

P73 and age-related diseases: is there any link with Parkinson Disease?
por: Grespi, Francesca, et al.
Publicado: (2012)

Metabolic pathways regulated by TAp73 in response to oxidative stress
por: Agostini, Massimiliano, et al.
Publicado: (2016)

Context is everything: extrinsic signalling and gain-of-function p53 mutants
por: Amelio, Ivano, et al.
Publicado: (2020)

ßNp63 controls cellular redox status
por: Annicchiarico-Petruzzelli, Margherita, et al.
Publicado: (2015)

MicroRNAs and p63 in epithelial stemness
por: Candi, E, et al.
Publicado: (2015)

Ultraconserved long non-coding RNA uc.63 in breast cancer
por: Marini, Alberto, et al.
Publicado: (2016)

ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma
por: Frezza, Valentina, et al.
Publicado: (2018)

MicroRNA-152 and -181a participate in human dermal fibroblasts senescence acting on cell adhesion and remodeling of the extra-cellular matrix
por: Mancini, Mara, et al.
Publicado: (2012)

p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms
por: Vikhreva, Polina, et al.
Publicado: (2018)

The “Sharp” blade against HIF-mediated metastasis
por: Amelio, Ivano, et al.
Publicado: (2012)

Damage limitation
por: Amelio, Ivano, et al.
Publicado: (2016)

Understanding p53 tumour suppressor network
por: Panatta, Emanuele, et al.
Publicado: (2021)

Do Mutations Turn p53 into an Oncogene?
por: Pitolli, Consuelo, et al.
Publicado: (2019)

Serine and glycine metabolism in cancer()
por: Amelio, Ivano, et al.
Publicado: (2014)

p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms
por: Pitolli, Consuelo, et al.
Publicado: (2019)

Two New p73 Splice Variants, γ and δ, with Different Transcriptional Activity
por: De Laurenzi, Vincenzo, et al.
Publicado: (1998)

Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense
por: D'Alessandro, Angelo, et al.
Publicado: (2014)

Cbx4: A new guardian of p63’s domain of epidermal control
por: Cohen, Idan, et al.
Publicado: (2016)

Exploiting tumour addiction with a serine and glycine-free diet
por: Amelio, Ivano, et al.
Publicado: (2017)

NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic network
por: Mammarella, Eleonora, et al.
Publicado: (2021)

Regulation of Adult Neurogenesis in Mammalian Brain
por: Niklison-Chirou, Maria Victoria, et al.
Publicado: (2020)

ZNF185 is a p53 target gene following DNA damage
por: Smirnov, Artem, et al.
Publicado: (2018)

Distinct interactors define the p63 transcriptional signature in epithelial development or cancer
por: Pecorari, Rosalba, et al.
Publicado: (2022)

Bispecific antibodies come to the aid of cancer immunotherapy
por: Amelio, Ivano, et al.
Publicado: (2021)

p53 regulates expression of nuclear envelope components in cancer cells
por: Panatta, Emanuele, et al.
Publicado: (2022)

p53 mutations define the chromatin landscape to confer drug tolerance in pancreatic cancer
por: Zampieri, Carlotta, et al.
Publicado: (2022)

Recent advances in cancer immunotherapy
por: Sun, Qiang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ijvbv8kt2qesbun89otu20osvs