Kinetochore localized Mad2 and Cdc20 is itself insufficient for triggering the mitotic checkpoint when Mps1 is low in Drosophila melanogaster neuroblasts

The relationships between the kinetochore and checkpoint control remain unresolved. Here, we report the characterization of the in vivo behavior of Cdc20 and Mad2 and the relevant spindle assembly checkpoint (SAC) functions in the neuroblasts of a Drosophila Mps1 weak allele (ald(B4–2)). ald(B4–2) t...

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Detalles Bibliográficos
Autores principales: Herriott, Ashleigh, Sweeney, Michele, Whitaker, Michael, Taggart, Michael, Huang, Jun-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562310/
https://www.ncbi.nlm.nih.gov/pubmed/23187806
http://dx.doi.org/10.4161/cc.22916

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