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PDGF is Required for Remyelination-Promoting IgM Stimulation of Oligodendrocyte Progenitor Cell Proliferation

BACKGROUND: Promotion of remyelination is a major goal in treating demyelinating diseases such as multiple sclerosis (MS). The recombinant human monoclonal IgM, rHIgM22, targets myelin and oligodendrocytes (OLs) and promotes remyelination in animal models of MS. It is unclear whether rHIgM22-mediate...

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Detalles Bibliográficos
Autores principales:	Watzlawik, Jens O., Warrington, Arthur E., Rodriguez, Moses
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562326/ https://www.ncbi.nlm.nih.gov/pubmed/23383310 http://dx.doi.org/10.1371/journal.pone.0055149

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