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Accumulation of Splice Variants and Transcripts in Response to PI3K Inhibition in T Cells

BACKGROUND: Measles virus (MV) causes T cell suppression by interference with phosphatidylinositol-3-kinase (PI3K) activation. We previously found that this interference affected the activity of splice regulatory proteins and a T cell inhibitory protein isoform was produced from an alternatively spl...

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Detalles Bibliográficos
Autores principales: Riedel, Alice, Mofolo, Boitumelo, Avota, Elita, Schneider-Schaulies, Sibylle, Meintjes, Ayton, Mulder, Nicola, Kneitz, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562341/
https://www.ncbi.nlm.nih.gov/pubmed/23383294
http://dx.doi.org/10.1371/journal.pone.0050695