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Two-stage meta-analysis of survival data from individual participants using percentile ratios
Methods for individual participant data meta-analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently, Siannis et al. (2010, Statistics in Medicine 29:3030–3045) proposed the use of percentile ratios as an alternative to hazard ratios. We describe a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562482/ https://www.ncbi.nlm.nih.gov/pubmed/22825835 http://dx.doi.org/10.1002/sim.5516 |
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author | Barrett, Jessica K Farewell, Vern T Siannis, Fotios Tierney, Jayne Higgins, Julian P T |
author_facet | Barrett, Jessica K Farewell, Vern T Siannis, Fotios Tierney, Jayne Higgins, Julian P T |
author_sort | Barrett, Jessica K |
collection | PubMed |
description | Methods for individual participant data meta-analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently, Siannis et al. (2010, Statistics in Medicine 29:3030–3045) proposed the use of percentile ratios as an alternative to hazard ratios. We describe a novel two-stage method for the meta-analysis of percentile ratios that avoids distributional assumptions at the study level. Copyright © 2012 John Wiley & Sons, Ltd. |
format | Online Article Text |
id | pubmed-3562482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-35624822013-02-07 Two-stage meta-analysis of survival data from individual participants using percentile ratios Barrett, Jessica K Farewell, Vern T Siannis, Fotios Tierney, Jayne Higgins, Julian P T Stat Med Special Issue Papers Methods for individual participant data meta-analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently, Siannis et al. (2010, Statistics in Medicine 29:3030–3045) proposed the use of percentile ratios as an alternative to hazard ratios. We describe a novel two-stage method for the meta-analysis of percentile ratios that avoids distributional assumptions at the study level. Copyright © 2012 John Wiley & Sons, Ltd. John Wiley & Sons, Ltd 2012-12-30 2012-07-24 /pmc/articles/PMC3562482/ /pubmed/22825835 http://dx.doi.org/10.1002/sim.5516 Text en Copyright © 2012 John Wiley & Sons, Ltd. http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation. |
spellingShingle | Special Issue Papers Barrett, Jessica K Farewell, Vern T Siannis, Fotios Tierney, Jayne Higgins, Julian P T Two-stage meta-analysis of survival data from individual participants using percentile ratios |
title | Two-stage meta-analysis of survival data from individual participants using percentile ratios |
title_full | Two-stage meta-analysis of survival data from individual participants using percentile ratios |
title_fullStr | Two-stage meta-analysis of survival data from individual participants using percentile ratios |
title_full_unstemmed | Two-stage meta-analysis of survival data from individual participants using percentile ratios |
title_short | Two-stage meta-analysis of survival data from individual participants using percentile ratios |
title_sort | two-stage meta-analysis of survival data from individual participants using percentile ratios |
topic | Special Issue Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562482/ https://www.ncbi.nlm.nih.gov/pubmed/22825835 http://dx.doi.org/10.1002/sim.5516 |
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