Cargando…

Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma

Congenital malignant melanoma (CMM) is a rare condition that is defined as malignant melanoma recognized at birth. CMM may develop in utero in one of three ways: (1) transmission by metastasis through the placenta from a mother with melanoma; (2) primary melanoma arising within a giant congenital me...

Descripción completa

Detalles Bibliográficos
Autores principales: Scalvenzi, Massimiliano, Palmisano, Franco, Cacciapuoti, Sara, Migliaro, Fiorella, Siano, Maria, Staibano, Stefania, Tornillo, Luigi, Costa, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562615/
https://www.ncbi.nlm.nih.gov/pubmed/23401804
http://dx.doi.org/10.1155/2013/473635
_version_ 1782258115237904384
author Scalvenzi, Massimiliano
Palmisano, Franco
Cacciapuoti, Sara
Migliaro, Fiorella
Siano, Maria
Staibano, Stefania
Tornillo, Luigi
Costa, Claudia
author_facet Scalvenzi, Massimiliano
Palmisano, Franco
Cacciapuoti, Sara
Migliaro, Fiorella
Siano, Maria
Staibano, Stefania
Tornillo, Luigi
Costa, Claudia
author_sort Scalvenzi, Massimiliano
collection PubMed
description Congenital malignant melanoma (CMM) is a rare condition that is defined as malignant melanoma recognized at birth. CMM may develop in utero in one of three ways: (1) transmission by metastasis through the placenta from a mother with melanoma; (2) primary melanoma arising within a giant congenital melanocytic naevus (GCMN); (3) primary de novo cutaneous CMM arising in utero. CMM can be confused clinically and histologically with benign proliferative melanocytic lesions such as giant congenital nevi. We describe the case of a patient presenting a GCMN with proliferative nodules, clinically and dermoscopically resembling a CMM, demonstrating the importance of caution in making a diagnosis of MM and highlighting the possibility that benign lesions as GCMN can mimic a malignant melanoma in this age group.
format Online
Article
Text
id pubmed-3562615
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-35626152013-02-11 Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma Scalvenzi, Massimiliano Palmisano, Franco Cacciapuoti, Sara Migliaro, Fiorella Siano, Maria Staibano, Stefania Tornillo, Luigi Costa, Claudia Case Rep Dermatol Med Case Report Congenital malignant melanoma (CMM) is a rare condition that is defined as malignant melanoma recognized at birth. CMM may develop in utero in one of three ways: (1) transmission by metastasis through the placenta from a mother with melanoma; (2) primary melanoma arising within a giant congenital melanocytic naevus (GCMN); (3) primary de novo cutaneous CMM arising in utero. CMM can be confused clinically and histologically with benign proliferative melanocytic lesions such as giant congenital nevi. We describe the case of a patient presenting a GCMN with proliferative nodules, clinically and dermoscopically resembling a CMM, demonstrating the importance of caution in making a diagnosis of MM and highlighting the possibility that benign lesions as GCMN can mimic a malignant melanoma in this age group. Hindawi Publishing Corporation 2013 2013-01-16 /pmc/articles/PMC3562615/ /pubmed/23401804 http://dx.doi.org/10.1155/2013/473635 Text en Copyright © 2013 Massimiliano Scalvenzi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Scalvenzi, Massimiliano
Palmisano, Franco
Cacciapuoti, Sara
Migliaro, Fiorella
Siano, Maria
Staibano, Stefania
Tornillo, Luigi
Costa, Claudia
Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma
title Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma
title_full Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma
title_fullStr Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma
title_full_unstemmed Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma
title_short Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma
title_sort giant congenital melanocytic naevus with proliferative nodules mimicking congenital malignant melanoma: a case report and review of the literature of congenital melanoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562615/
https://www.ncbi.nlm.nih.gov/pubmed/23401804
http://dx.doi.org/10.1155/2013/473635
work_keys_str_mv AT scalvenzimassimiliano giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma
AT palmisanofranco giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma
AT cacciapuotisara giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma
AT migliarofiorella giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma
AT sianomaria giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma
AT staibanostefania giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma
AT tornilloluigi giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma
AT costaclaudia giantcongenitalmelanocyticnaevuswithproliferativenodulesmimickingcongenitalmalignantmelanomaacasereportandreviewoftheliteratureofcongenitalmelanoma