Cargando…

Neuropeptide Y receptors: how to get subtype selectivity

The neuropeptide Y (NPY) system is a multireceptor/multiligand system consisting of four receptors in humans (hY(1), hY(2), hY(4), hY(5)) and three agonists (NPY, PYY, PP) that activate these receptors with different potency. The relevance of this system in diseases like obesity or cancer, and the d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pedragosa-Badia, Xavier, Stichel, Jan, Beck-Sickinger, Annette G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563083/ https://www.ncbi.nlm.nih.gov/pubmed/23382728 http://dx.doi.org/10.3389/fendo.2013.00005

Ejemplares similares

Cell-Free Expression and Photo-Crosslinking of the Human Neuropeptide Y(2) Receptor
por: Kögler, Lisa Maria, et al.
Publicado: (2019)

Characterisation of Neuropeptide Y Receptor Subtypes by Synthetic NPY Analogues and by Anti-receptor Antibodies‡
por: Eckard, Christophe P., et al.
Publicado: (2001)

Discovery of Small-Molecule Modulators of the Human Y(4) Receptor
por: Sliwoski, Gregory, et al.
Publicado: (2016)

Structural basis for ligand recognition of the neuropeptide Y Y(2) receptor
por: Tang, Tingting, et al.
Publicado: (2021)

Select Neuropeptides and their G-Protein Coupled Receptors in Caenorhabditis Elegans and Drosophila Melanogaster
por: Bendena, William G., et al.
Publicado: (2012)

The Conformational Equilibrium of the Neuropeptide Y2 Receptor in Bilayer Membranes
por: Krug, Ulrike, et al.
Publicado: (2020)

Unusually persistent Gα(i)-signaling of the neuropeptide Y(2) receptor depletes cellular G(i/o) pools and leads to a G(i)-refractory state
por: Ziffert, Isabelle, et al.
Publicado: (2020)

Neuropeptide G Protein-Coupled Receptors as Oncotargets
por: Moody, Terry W., et al.
Publicado: (2018)

The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation
por: Vogel, Alexander, et al.
Publicado: (2020)

Neuropeptide Y in Alcohol Addiction and Affective Disorders
por: Thorsell, Annika, et al.
Publicado: (2017)

Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides
por: Chastel, Adrien, et al.
Publicado: (2020)

Neuropeptide W
por: Takenoya, Fumiko, et al.
Publicado: (2012)

Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b
por: Sundström, Görel, et al.
Publicado: (2013)

Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates
por: Fadda, Melissa, et al.
Publicado: (2019)

Current Insights Into the Role of Neuropeptide Y in Skin Physiology and Pathology
por: Anderson, Zoya T., et al.
Publicado: (2022)

Insight Into Mosquito GnRH-Related Neuropeptide Receptor Specificity Revealed Through Analysis of Naturally Occurring and Synthetic Analogs of This Neuropeptide Family
por: Wahedi, Azizia, et al.
Publicado: (2019)

Neuropeptide GPCRs in Neuroendocrinology
por: Vaudry, Hubert, et al.
Publicado: (2014)

Structural basis of ligand binding modes at the neuropeptide Y Y(1) receptor
por: Yang, Zhenlin, et al.
Publicado: (2018)

Analysis of Pigment-Dispersing Factor Neuropeptides and Their Receptor in a Velvet Worm
por: Martin, Christine, et al.
Publicado: (2020)

Evolution and Potential Function in Molluscs of Neuropeptide and Receptor Homologues of the Insect Allatostatins
por: Li, Zhi, et al.
Publicado: (2021)

Effects of Starvation on Brain Short Neuropeptide F-1, -2, and -3 Levels and Short Neuropeptide F Receptor Expression Levels of the Silkworm, Bombyx mori
por: Nagata, Shinji, et al.
Publicado: (2012)

Social bonding: regulation by neuropeptides
por: Lieberwirth, Claudia, et al.
Publicado: (2014)

Neuropeptide GPCRs in C. elegans
por: Frooninckx, Lotte, et al.
Publicado: (2012)

Update on the Role of Neuropeptide Y and Other Related Factors in Breast Cancer and Osteoporosis
por: Lin, Shu-ting, et al.
Publicado: (2021)

Five Neuropeptide Ligands Meet One Receptor: How Does This Tally? A Structure-Activity Relationship Study Using Adipokinetic Bioassays With the Sphingid Moth, Hippotion eson
por: Marco, Heather G., et al.
Publicado: (2019)

Regulation of Neurosteroid Biosynthesis by Neurotransmitters and Neuropeptides
por: Do Rego, Jean Luc, et al.
Publicado: (2012)

Evolution of Neuropeptide Precursors in Polyneoptera (Insecta)
por: Bläser, Marcel, et al.
Publicado: (2020)

Female reproductive functions of the neuropeptide PACAP
por: Koppan, Miklos, et al.
Publicado: (2022)

Reproductive roles of the vasopressin/oxytocin neuropeptide family in teleost fishes
por: Mennigen, Jan A., et al.
Publicado: (2022)

Identification and Characterization of Neuropeptides and Their G Protein-Coupled Receptors (GPCRs) in the Cowpea Aphid Aphis craccivora
por: Li, Xiao, et al.
Publicado: (2020)

Arginine Vasotocin, the Social Neuropeptide of Amphibians and Reptiles
por: Wilczynski, Walter, et al.
Publicado: (2017)

Editorial: Neuropeptides and Behavior: From Motivation to Psychopathology
por: Suchecki, Deborah, et al.
Publicado: (2017)

Function and Distribution of the Wamide Neuropeptide Superfamily in Metazoans
por: Williams, Elizabeth A.
Publicado: (2020)

Comparative Aspects of Structure and Function of Cnidarian Neuropeptides
por: Takahashi, Toshio
Publicado: (2020)

Editorial: Neuropeptide GPCRs in neuroendocrinology, Volume II
por: Vaudry, Hubert, et al.
Publicado: (2023)

The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features
por: Castel, Hélène, et al.
Publicado: (2017)

Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes
por: A. Tindall, Catherine, et al.
Publicado: (2021)

Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation
por: Jhamandas, Jack H., et al.
Publicado: (2013)

Brain neuropeptides in central ventilatory and cardiovascular regulation in trout
por: Le Mével, Jean-Claude, et al.
Publicado: (2012)

Glucocorticoid Receptor Antagonism Upregulates Somatostatin Receptor Subtype 2 Expression in ACTH-Producing Neuroendocrine Tumors: New Insight Based on the Selective Glucocorticoid Receptor Modulator Relacorilant
por: Pivonello, Rosario, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tetoa8pq7pb76ahdumhj2ru4ks