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Type 1 insulin-like growth factor receptor targeted therapies in pediatric cancer

Data from over 20 years ago demonstrated potential use for insulin-like growth factor (IGF) signaling modulators, specifically with IGF-1R antagonists, in a variety of pediatric and adolescent cancers, particularly in sarcomas. However, in spite of promising preclinical data, IGF-1R inhibitors have...

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Detalles Bibliográficos
Autores principales:	Wagner, Michael J., Maki, Robert G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563098/ https://www.ncbi.nlm.nih.gov/pubmed/23383402 http://dx.doi.org/10.3389/fonc.2013.00009

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