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Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population

The metabolic changes present in the metabolic syndrome (MetS) have been associated with increased risk of pancreatic and colon cancers; however, there is little information about the association between MetS and cervical cancer risk. We performed a case-control study using data from the National He...

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Autores principales: Penaranda, Eribeth K., Shokar, Navkiran, Ortiz, Melchor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563171/
https://www.ncbi.nlm.nih.gov/pubmed/23431471
http://dx.doi.org/10.1155/2013/840964
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author Penaranda, Eribeth K.
Shokar, Navkiran
Ortiz, Melchor
author_facet Penaranda, Eribeth K.
Shokar, Navkiran
Ortiz, Melchor
author_sort Penaranda, Eribeth K.
collection PubMed
description The metabolic changes present in the metabolic syndrome (MetS) have been associated with increased risk of pancreatic and colon cancers; however, there is little information about the association between MetS and cervical cancer risk. We performed a case-control study using data from the National Health and Nutrition Examination Survey (NHANES) between 1999–2010. We identified women 21 years of age and older, of which an estimated 585,924 (2.3% of the sample) self-reported a history of cervical cancer (cases). About half (48.6%) of cases and 33.2% of controls met criteria for MetS. Logistic regression analysis showed increased odds of history of cervical cancer among women with MetS (OR = 1.9; 95% CI 1.06, 3.42; P value ≤ 0.05) for the risk of history of cervical cancer among women with MetS while adjusting for other known risk factors (high number of lifetime sexual partners, multiparty, history of hormonal contraceptive use, and history of smoking) (AOR = 1.82; 95% CI 1.02, 3.26; P value ≤ 0.05). In this US surveyed population we found increased odds of history of cervical cancer among subjects with MetS.
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spelling pubmed-35631712013-02-21 Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population Penaranda, Eribeth K. Shokar, Navkiran Ortiz, Melchor ISRN Oncol Research Article The metabolic changes present in the metabolic syndrome (MetS) have been associated with increased risk of pancreatic and colon cancers; however, there is little information about the association between MetS and cervical cancer risk. We performed a case-control study using data from the National Health and Nutrition Examination Survey (NHANES) between 1999–2010. We identified women 21 years of age and older, of which an estimated 585,924 (2.3% of the sample) self-reported a history of cervical cancer (cases). About half (48.6%) of cases and 33.2% of controls met criteria for MetS. Logistic regression analysis showed increased odds of history of cervical cancer among women with MetS (OR = 1.9; 95% CI 1.06, 3.42; P value ≤ 0.05) for the risk of history of cervical cancer among women with MetS while adjusting for other known risk factors (high number of lifetime sexual partners, multiparty, history of hormonal contraceptive use, and history of smoking) (AOR = 1.82; 95% CI 1.02, 3.26; P value ≤ 0.05). In this US surveyed population we found increased odds of history of cervical cancer among subjects with MetS. Hindawi Publishing Corporation 2013-01-21 /pmc/articles/PMC3563171/ /pubmed/23431471 http://dx.doi.org/10.1155/2013/840964 Text en Copyright © 2013 Eribeth K. Penaranda et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Penaranda, Eribeth K.
Shokar, Navkiran
Ortiz, Melchor
Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population
title Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population
title_full Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population
title_fullStr Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population
title_full_unstemmed Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population
title_short Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population
title_sort relationship between metabolic syndrome and history of cervical cancer among a us national population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563171/
https://www.ncbi.nlm.nih.gov/pubmed/23431471
http://dx.doi.org/10.1155/2013/840964
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