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Effect of High-Dose or Split-Dose Artesunate on Parasite Clearance in Artemisinin-Resistant Falciparum Malaria
Background. The emergence of Plasmodium falciparum resistance to artemisinins on the Cambodian and Myanmar-Thai borders poses severe threats to malaria control. We investigated whether increasing or splitting the dose of the short-half-life drug artesunate improves parasite clearance in falciparum m...
Autores principales: | Das, Debashish, Tripura, Rupam, Phyo, Aung Pyae, Lwin, Khin Maung, Tarning, Joel, Lee, Sue J., Hanpithakpong, Warunee, Stepniewska, Kasia, Menard, Didier, Ringwald, Pascal, Silamut, Kamolrat, Imwong, Mallika, Chotivanich, Kesinee, Yi, Poravuth, Day, Nicholas P. J., Lindegardh, Niklas, Socheat, Duong, Nguon, Chea, White, Nicholas J., Nosten, François, Dondorp, Arjen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563392/ https://www.ncbi.nlm.nih.gov/pubmed/23175556 http://dx.doi.org/10.1093/cid/cis958 |
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