Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions

BACKGROUND: Cancer, much like most human disease, is routinely studied by utilizing model organisms. Of these model organisms, mice are often dominant. However, our assumptions of functional equivalence fail to consider the opportunity for divergence conferred by ~180 Million Years (MY) of independe...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Claire C, Shakya, Kabita, Webb, Andrew, Walsh, Thomas A, Lynch, Mark, Loscher, Christine E, Ruskin, Heather J, O’Connell, Mary J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563467/
https://www.ncbi.nlm.nih.gov/pubmed/22788692
http://dx.doi.org/10.1186/1471-2148-12-114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563467/
https://www.ncbi.nlm.nih.gov/pubmed/22788692
http://dx.doi.org/10.1186/1471-2148-12-114

Ejemplares similares