Cargando…

Inhibition of TTR Aggregation-Induced Cell Death – A New Role for Serum Amyloid P Component

BACKGROUND: Serum amyloid P component (SAP) is a glycoprotein that is universally found associated with different types of amyloid deposits. It has been suggested that it stabilizes amyloid fibrils and therefore protects them from proteolytic degradation. METHODOLOGY/PRINCIPAL FINDINGS: In this pape...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andersson, Karin, Pokrzywa, Malgorzata, Dacklin, Ingrid, Lundgren, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563535/ https://www.ncbi.nlm.nih.gov/pubmed/23390551 http://dx.doi.org/10.1371/journal.pone.0055766

Ejemplares similares

Uptake of Aggregating Transthyretin by Fat Body in a Drosophila Model for TTR-Associated Amyloidosis
por: Pokrzywa, Malgorzata, et al.
Publicado: (2010)

Treatment of transthyretin (TTR) amyloid cardiomyopathy with an antisense oligonucleotide inhibitor of TTR synthesis
por: Benson, Merrill D, et al.
Publicado: (2015)

Single injection of small-molecule amyloid accelerator results in cell death of nigral dopamine neurons in mice
por: Chermenina, Maria, et al.
Publicado: (2015)

Transthyretin familial amyloid polyneuropathy (TTR‐FAP): Parameters for early diagnosis
por: Escolano‐Lozano, Fabiola, et al.
Publicado: (2017)

A phase 3 clinical trial with ISIS-TTRRx, a 2nd-generation antisense oligonucleotide targeting transthyretin (TTR), for the treatment of TTR amyloid cardiomyopathy
por: Millns, Helen, et al.
Publicado: (2015)

Teachings from the French database of TTR familial amyloidotic polyneuropathy (TTR-FAP): large genetic and phenotypic heterogeneity, usefulness of TTR gene testing.
por: Adams, David, et al.
Publicado: (2015)

Sixty years of transthyretin familial amyloid polyneuropathy (TTR-FAP) in Europe: where are we now? A European network approach to defining the epidemiology and management patterns for TTR-FAP
por: Parman, Yesim, et al.
Publicado: (2016)

Clinicopathological correlations of sural nerve biopsies in TTR Val30Met familial amyloid polyneuropathy
por: Fernandes, Armindo, et al.
Publicado: (2019)

Population diversity of the genetically determined TTR expression in human tissues and its implications in TTR amyloidosis
por: Iorio, Andrea, et al.
Publicado: (2017)

Identification of a new variant of TTR involved in familial amyloid cardiomyopathy (FAC) in Brazil: from the patient to the protein
por: Ferreira, Priscila, et al.
Publicado: (2015)

TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity
por: Fan, Yujuan, et al.
Publicado: (2017)

Antibodies to human serum amyloid P component eliminate visceral amyloid deposits
por: Bodin, Karl, et al.
Publicado: (2010)

The diagnostic accuracy of Sudoscan in TTR-FAP
por: Castro, Jose, et al.
Publicado: (2015)

Therapeutic education programme in TTR-FAP
por: Théaudin, Marie, et al.
Publicado: (2015)

Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD
por: Rios, Xabier, et al.
Publicado: (2019)

Fibronectin and C4-binding protein are selectively bound by aggregated amyloid P component
por: DeBeer, FC, et al.
Publicado: (1981)

The Paradoxical Effects of Serum Amyloid-P Component on Disseminated Candidiasis
por: Klotz, Stephen A., et al.
Publicado: (2022)

Serum amyloid P component: a new biomarker for low sperm concentration?
por: Sonesson, Annika, et al.
Publicado: (2021)

Vitreous Amyloidosis as the Presenting Symptom of Familial Amyloid Polyneuropathy TTR Val30Met in a Portuguese Patient
por: Seca, Mariana, et al.
Publicado: (2014)

Transthyretin familial amyloid polyneuropathy (TTR-FAP) in Mallorca: a comparison between late- and early-onset disease
por: Raya-Cruz, Manuel, et al.
Publicado: (2015)

Characterization of conformation-specific, human-derived monoclonal antibodies against TTR aggregates with potential for diagnostic and therapeutic use
por: Michalon, Aubin, et al.
Publicado: (2015)

Serum amyloid P inhibits granulocyte adhesion
por: Maharjan, Anu S, et al.
Publicado: (2013)

Retinal and choroidal vascular abnormalities in TTR-FAP
por: Rousseau, Antoine, et al.
Publicado: (2015)

Preimplantation genetic diagnosis for TTR-FAP in Portugal
por: Carvalho, Filipa
Publicado: (2015)

Clinical Presentation, Diagnosis and Treatment of TTR Amyloidosis
por: Kapoor, Mahima, et al.
Publicado: (2019)

TTR: Time in Therapeutic Range or “The Troublesome Report”?
por: Reiffel, James A.
Publicado: (2019)

Binding specificity of serum amyloid P component for the pyruvate acetal of galactose
Publicado: (1984)

Nucleosome binding by serum amyloid P component from SLE patients
por: Heegaard, NHH, et al.
Publicado: (2001)

Transthyretin-Related Familial Amyloid Polyneuropathy (TTR-FAP): A Single-Center Experience in Sicily, an Italian Endemic Area
por: Mazzeo, Anna, et al.
Publicado: (2015)

Characterization of the Oligomerization and Aggregation of Human Serum Amyloid A
por: Patke, Sanket, et al.
Publicado: (2013)

Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson’s disease
por: Pokrzywa, Małgorzata, et al.
Publicado: (2017)

Aggregation of Mouse Serum Amyloid A Protein Was Promoted by Amyloid-Enhancing Factors with the More Genetically Homologous Serum Amyloid A
por: Lin, Xuguang, et al.
Publicado: (2021)

Mechanisms for the inhibition of amyloid aggregation by small ligands
por: Ramazzotti, Matteo, et al.
Publicado: (2016)

Aqueous humor erythropoietin levels in open-angle glaucoma patients with and without TTR V30M familial amyloid polyneuropathy
por: Beirão, João M., et al.
Publicado: (2014)

Curcumin could reduce the monomer of TTR with Tyr114Cys mutation via autophagy in cell model of familial amyloid polyneuropathy
por: Li, Hui, et al.
Publicado: (2014)

Extracellular Matrix Markers for Disease Progression and Follow-Up of Therapies in Familial Amyloid Polyneuropathy V30M TTR-Related
por: Cardoso, I., et al.
Publicado: (2008)

Non-invasive risk stratification of patients with TTR amyloidosis
por: Scherer, Katrin A, et al.
Publicado: (2013)

Neurophysiological pitfalls in TTR-FAP Val30Met
por: Conceição, Isabel, et al.
Publicado: (2015)

Management of stage 1 TTR FAP: French experience
por: Adams, David, et al.
Publicado: (2015)

Neurophysiological pitfalls in TTR-FAP Val30Met
por: Conceição, Isabel, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_g1ir80ireqre82a38uf4pmgetg