Prevalence, Specificity and Determinants of Lipid-Interacting PDZ Domains from an In-Cell Screen and In Vitro Binding Experiments

BACKGROUND: PDZ domains are highly abundant protein-protein interaction modules involved in the wiring of protein networks. Emerging evidence indicates that some PDZ domains also interact with phosphoinositides (PtdInsPs), important regulators of cell polarization and signaling. Yet our knowledge on...

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Detalles Bibliográficos
Autores principales: Ivarsson, Ylva, Wawrzyniak, Anna Maria, Kashyap, Rudra, Polanowska, Jolanta, Betzi, Stéphane, Lembo, Frédérique, Vermeiren, Elke, Chiheb, Driss, Lenfant, Nicolas, Morelli, Xavier, Borg, Jean-Paul, Reboul, Jérôme, Zimmermann, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563628/
https://www.ncbi.nlm.nih.gov/pubmed/23390500
http://dx.doi.org/10.1371/journal.pone.0054581

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