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Effects of the Endpoint Adjudication Process on the Results of a Randomised Controlled Trial: The ADVANCE Trial

BACKGROUND: Endpoint adjudication committees (EPAC) are widely used in clinical trials. The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial (Trial registration: ClinicalTrials.gov NCT00145925). METHODS AND FINDINGS:...

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Detalles Bibliográficos
Autores principales: Hata, Jun, Arima, Hisatomi, Zoungas, Sophia, Fulcher, Greg, Pollock, Carol, Adams, Mark, Watson, John, Joshi, Rohina, Kengne, Andre Pascal, Ninomiya, Toshiharu, Anderson, Craig, Woodward, Mark, Patel, Anushka, Mancia, Giuseppe, Poulter, Neil, MacMahon, Stephen, Chalmers, John, Neal, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563633/
https://www.ncbi.nlm.nih.gov/pubmed/23390553
http://dx.doi.org/10.1371/journal.pone.0055807