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Lipopolysaccharides with Acylation Defects Potentiate TLR4 Signaling and Shape T Cell Responses
Lipopolysaccharides or endotoxins are components of Gram-negative enterobacteria that cause septic shock in mammals. However, a LPS carrying hexa-acyl lipid A moieties is highly endotoxic compared to a tetra-acyl LPS and the latter has been considered as an antagonist of hexa-acyl LPS-mediated TLR4...
Autores principales: | Martirosyan, Anna, Ohne, Yoichiro, Degos, Clara, Gorvel, Laurent, Moriyón, Ignacio, Oh, Sangkon, Gorvel, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563657/ https://www.ncbi.nlm.nih.gov/pubmed/23390517 http://dx.doi.org/10.1371/journal.pone.0055117 |
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