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Adaptation to Experimental Jet-Lag in R6/2 Mice despite Circadian Dysrhythmia
The R6/2 transgenic mouse model of Huntington’s disease (HD) shows a disintegration of circadian rhythms that can be delayed by pharmacological and non-pharmacological means. Since the molecular machinery underlying the circadian clocks is intact, albeit progressively dysfunctional, we wondered if l...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563662/ https://www.ncbi.nlm.nih.gov/pubmed/23390510 http://dx.doi.org/10.1371/journal.pone.0055036 |