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Structural basis of tubulin tyrosination by tubulin tyrosine ligase

Tubulin tyrosine ligase (TTL) catalyzes the post-translational retyrosination of detyrosinated α-tubulin. Despite the indispensable role of TTL in cell and organism development, its molecular mechanism of action is poorly understood. By solving crystal structures of TTL in complex with tubulin, we h...

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Detalles Bibliográficos
Autores principales:	Prota, Andrea E., Magiera, Maria M., Kuijpers, Marijn, Bargsten, Katja, Frey, Daniel, Wieser, Mara, Jaussi, Rolf, Hoogenraad, Casper C., Kammerer, Richard A., Janke, Carsten, Steinmetz, Michel O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563685/ https://www.ncbi.nlm.nih.gov/pubmed/23358242 http://dx.doi.org/10.1083/jcb.201211017

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