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Experimental approaches to identify cellular G-quadruplex structures and functions

Guanine-rich nucleic acids can fold into non-canonical DNA secondary structures called G-quadruplexes. The formation of these structures can interfere with the biology that is crucial to sustain cellular homeostases and metabolism via mechanisms that include transcription, translation, splicing, tel...

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Detalles Bibliográficos
Autores principales: Di Antonio, Marco, Rodriguez, Raphaël, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563962/
https://www.ncbi.nlm.nih.gov/pubmed/22343041
http://dx.doi.org/10.1016/j.ymeth.2012.01.008