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Estimating Empirical Codon Hidden Markov Models

Empirical codon models (ECMs) estimated from a large number of globular protein families outperformed mechanistic codon models in their description of the general process of protein evolution. Among other factors, ECMs implicitly model the influence of amino acid properties and multiple nucleotide s...

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Detalles Bibliográficos
Autores principales: De Maio, Nicola, Holmes, Ian, Schlötterer, Christian, Kosiol, Carolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563974/
https://www.ncbi.nlm.nih.gov/pubmed/23188590
http://dx.doi.org/10.1093/molbev/mss266