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The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress

The mouse hippocampal cell line HT22 is an excellent model for studying the consequences of endogenous oxidative stress. Addition of extracellular glutamate depletes the cells of glutathione (GSH) by blocking the glutamate−cystine antiporter system x(c)(−). GSH is the main antioxidant in neurons and...

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Detalles Bibliográficos
Autores principales:	Henke, N, Albrecht, P, Bouchachia, I, Ryazantseva, M, Knoll, K, Lewerenz, J, Kaznacheyeva, E, Maher, P, Methner, A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564003/ https://www.ncbi.nlm.nih.gov/pubmed/23348584 http://dx.doi.org/10.1038/cddis.2012.216

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