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Fundamental roles of the innate-like repertoire of natural antibodies in immune homeostasis

The composition of the early immune repertoire is biased with prominent expression of spontaneously arising B cell clones that produce IgM with recurrent and often autoreactive binding specificities. Amongst these naturally arising antibodies (NAbs) are IgM antibodies that specifically recognized am...

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Detalles Bibliográficos
Autores principales: Vas, Jaya, Grönwall, Caroline, Silverman, Gregg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564042/
https://www.ncbi.nlm.nih.gov/pubmed/23386848
http://dx.doi.org/10.3389/fimmu.2013.00004