Cargando…

Cellular Aspects of Prion Replication In Vitro

Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative disorders in mammals that are caused by unconventional agents predominantly composed of aggregated misfolded prion protein (PrP). Prions self-propagate by recruitment of host-encoded PrP into highly ordere...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grassmann, Andrea, Wolf, Hanna, Hofmann, Julia, Graham, James, Vorberg, Ina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564126/ https://www.ncbi.nlm.nih.gov/pubmed/23340381 http://dx.doi.org/10.3390/v5010374

Ejemplares similares

Life cycle of cytosolic prions
por: Hofmann, Julia, et al.
Publicado: (2013)

All the Same? The Secret Life of Prion Strains within Their Target Cells
por: Vorberg, Ina M.
Publicado: (2019)

Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles
por: Liu, Shu, et al.
Publicado: (2016)

Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins
por: Krauss, Sybille, et al.
Publicado: (2013)

Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance
por: Duernberger, Yvonne, et al.
Publicado: (2018)

Genetic human prion disease modelled in PrP transgenic Drosophila
por: Thackray, Alana M., et al.
Publicado: (2017)

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie
por: Wolf, Hanna, et al.
Publicado: (2015)

Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo
por: Hafner-Bratkovič, Iva, et al.
Publicado: (2011)

Prion strains depend on different endocytic routes for productive infection
por: Fehlinger, Andrea, et al.
Publicado: (2017)

In vitro replication highlights the mutability of prions
por: Vanni, Ilaria, et al.
Publicado: (2014)

Prions on the run: How extracellular vesicles serve as delivery vehicles for self-templating protein aggregates
por: Liu, Shu, et al.
Publicado: (2017)

Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein
por: Makarava, Natallia, et al.
Publicado: (2018)

Correction to: preserving prion strain identity upon replication of prions in vitro using recombinant prion protein
por: Makarava, Natallia, et al.
Publicado: (2018)

Direct Observation of Murine Prion Protein Replication in Vitro
por: Sang, Jason C., et al.
Publicado: (2018)

Entropic Bristles Tune the Seeding Efficiency of Prion-Nucleating Fragments
por: Michiels, Emiel, et al.
Publicado: (2020)

α-Cleavage of cellular prion protein
por: Liang, Jingjing, et al.
Publicado: (2012)

The Cellular Prion Protein and the Hallmarks of Cancer
por: Mouillet-Richard, Sophie, et al.
Publicado: (2021)

Intercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells
por: Revilla-García, Aida, et al.
Publicado: (2020)

Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process?
por: Igel-Egalon, Angélique, et al.
Publicado: (2019)

Studies on Prion Replication in Spleen
por: Raeber, Alex J., et al.
Publicado: (2001)

Cellular Prion Protein: From Physiology to Pathology
por: Yusa, Sei-ichi, et al.
Publicado: (2012)

Pharmacological Agents Targeting the Cellular Prion Protein
por: Barreca, Maria Letizia, et al.
Publicado: (2018)

The biological function of the cellular prion protein: an update
por: Wulf, Marie-Angela, et al.
Publicado: (2017)

Prion replication environment defines the fate of prion strain adaptation
por: Katorcha, Elizaveta, et al.
Publicado: (2018)

Cellular, Molecular, and Physiological Aspects of In Vitro Plant Regeneration
por: Bidabadi, Siamak Shirani, et al.
Publicado: (2020)

Prion-like aspects of cerebral amyloidosis
por: Jucker, Mathias, et al.
Publicado: (2013)

Genetic aspects of human prion diseases
por: Appleby, Brian S., et al.
Publicado: (2022)

Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication
por: Frontzek, Karl, et al.
Publicado: (2016)

Inhibition of cholesterol recycling impairs cellular PrP(Sc) propagation
por: Gilch, Sabine, et al.
Publicado: (2009)

Prion propagation in vitro: are we there yet?
por: Ryou, Chongsuk, et al.
Publicado: (2008)

In vitro Modeling of Prion Strain Tropism
por: Levavasseur, Etienne, et al.
Publicado: (2019)

Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions
por: Mays, Charles E., et al.
Publicado: (2022)

Prion propagation and cellular dysfunction in prion disease: Disconnecting the dots
por: Foliaki, Simote T., et al.
Publicado: (2023)

Sialylation of the prion protein glycans controls prion replication rate and glycoform ratio
por: Katorcha, Elizaveta, et al.
Publicado: (2015)

Contrasting Effects of Two Lipid Cofactors of Prion Replication on the Conformation of the Prion Protein
por: Srivastava, Saurabh, et al.
Publicado: (2015)

Lesion of the Olfactory Epithelium Accelerates Prion Neuroinvasion and Disease Onset when Prion Replication Is Restricted to Neurons
por: Crowell, Jenna, et al.
Publicado: (2015)

A New Take on Prion Protein Dynamics in Cellular Trafficking
por: Alves, Rodrigo Nunes, et al.
Publicado: (2020)

The Quest for Cellular Prion Protein Functions in the Aged and Neurodegenerating Brain
por: Gavín, Rosalina, et al.
Publicado: (2020)

The Role of Cellular Prion Protein in Promoting Stemness and Differentiation in Cancer
por: Ryskalin, Larisa, et al.
Publicado: (2021)

The Cellular Prion Protein: A Promising Therapeutic Target for Cancer
por: Go, Gyeongyun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0fbg76ff24b65ckut4p5m7n46q